>> download Final Program (pdf) >> download Final Program with Abstracts (pdf, 5.5 MB) _____________________________________________________________________
Tuesday
April 8
15:00 - 16:30 Registration
16:30 - 17:00 Welcome Cocktail
17:00 - 19:00 Symposium 1
Rapid cross-talk between synaptic receptors: A key path of synaptic plasticity
Chair: Dmitri Rusakov (UK)
Dmitri Rusakov (UK) A sub-millisecond mGluR-NMDAR dialog triggering LTP
Julie Perroy (France) Cross-talk between
glutamate receptors
Antoine Triller (France) Control of synaptic strength by gypherin
Tobias Böckers (Germany) Autistic-like behaviours linked to the ProSAP/Shank function
Wednesday
April 9 Morning
08:15 – 09:00 Keynote Lecture 1
Herwig Baier (Germany) Retinal ganglion cell diversity creates separate visual processing channels that are tailored to behavioral output
09:00 - 11:00 Symposium 2
Functions of lyso-phosphatidic acid (LPA) signaling pathways in the CNS
Chair: Robert Nitsch (Germany)
Orly Reiner (Israel) Novel activities of autotaxin (ATX) in neuronal progenitors of the cerebral cortex
Johannes Vogt (Germany) Control of early
neuronal activity by synaptic phospholipids governs connectivity and memory
Andrew J. Morris (USA) Role of lysophosphatidic acid in traumatic brain injury
Robert Nitsch (Germany) Altered synaptic lipid signaling affects cortical information processing involved in psychiatric disorders
11:00 - 11:20 Coffee Break
11:20 - 13:20 Symposium 3
Multivariate and genome-wide approaches in imaging genetics
Chair: Gunter Schumann (UK)
Jianfeng Feng (UK) Brain-wide association study of resting state activity identifies functional links associated with psychiatric disorders
Jean-Luc Martinot (France) Imaging brain microstructure in mood disorders
Sylvane Desrivières (UK) Transcriptional control of neural development: Impact on brain structure and cognition
Gunter Schumann (UK) Genome-wide methylation analysis of monozygotic twins identifies association of protein phosphatase, Mg2+/Mn2+ dependent, 1G (PPM1G) hypermethylation with alcohol use disorder and measures of impulsiveness
Wednesday
April 9 Afternoon
13:20 - 15:20 Symposium 4
Glutamatergic transmission in schizophrenia
Chair: Robert Schwarcz (USA)
Christine Konradi (USA) Hippocampal interneurons and mitochondrial abnormalities in psychotic disorders
Joseph Coyle (USA) Serine racemase knockout mice: A mouse model of NMDA receptor hypofunction
Robert Schwarcz (USA) The role of endogenous kynurenic acid in hippocampal function and
dysfunction
W. Wolfgang Fleischhacker (Austria) Glutamatergic agents in the management of the symptoms of schizophrenia
Wednesday
April 9 Evening
16:00 – 18:00 Symposium 5
Learning-related dynamics in neuronal circuits in vivo
Chairs: Sonja Hofer (Switzerland) and Mark Hübener (Germany)
Adi Mizrahi (Israel) Structural and functional plasticity of adult born neurons in the mouse olfactory bulb
Florian Engert (USA) Neural circuits underlying operant learning in larval zebrafish
Tobias Rose (Germany) Neurons in visual cortex retain a memory of their inputs after monocular deprivation
Sonja Hofer (Switzerland) Neural dynamics in visual cortex during learning
18:00 - 18:20 Coffee Break
18:20 - 19:05 Special Guest Lecture
Petra Schwille (Germany) Divide and conquer - synthetic biology of cell division
19:05 – 20:30 Poster Session (List of posters at the bottom of this page)
Thursday
April 10 Morning
08:15 - 09:00 Keynote Lecture 2
Zach Mainen (Portugal) Neural circuits for spontaneous action timing in the frontal cortex
09:00 - 11:00 Symposium 6
Nanophysiology of presynaptic Ca2+ signaling
Chair: Tobias Moser (Germany)
Erwin Neher (Germany) Ca++-handling and superpriming at the Calyx of Held
Jakob Neef (Germany) Number, topography and coupling to release of Ca2+ channels at hair cell active zones
Tomoyuki Takahashi (Japan) Perimeter Ca2+ channel coupling to transmitter release at developing calyces of Held
Annalisa Scimemi (USA) Number and organization of Ca2+ channels in the active zone of Schaffer collateral synapses
Peter Jonas (Austria) Loose coupling between Ca2+ channels and release sensors enables presynaptic plasticity at a cortical glutamatergic synapse
11:00 - 11:20 Coffee Break
11:20 - 13:20 Symposium 7
ISN Symposium: Mitochondrial dysfunction in Parkinson’s disease: Failure of protein quality control
Chairs: Jörg Schulz (Germany) and Philipp Kahle (Germany)
Richard J. Youle (USA) Role of PINK1 and Parkin on mitochondrial QC in vitro and in vivo
Philipp Kahle (Germany) UBE2N, UBE2L3 and UBE2D2/3 ubiquitin-conjugating enzymes are essential for parkin-dependent mitophagy
Konstanze Winklhofer (Germany) Parkin
maintains mitochondrial integrity via linear ubiquitination of NEMO
Aaron Voigt (Germany) TRAP1, a new player in Parkinson’s disease
13:20 - 15:20 Symposium 8
NeuroBioengineering: New strategies targeting diverse neural cells for regenerative neurobiology
Chairs: Phil Beart (Australia) and Eva Sykova (Czech Republic)
Eva Sykova (Czech Republic) Stem cells and
biomaterials for treatment of CNS diseases
Sarka Kubinova (Czech Republic) Advanced methods for nervous tissue engineering
Sue Barnett (UK) Can scaffold design affect CNS myelination?
Philip Beart (Australia) Therapeutic potential of bioengineering strategies targeting astrocytes
Thursday
April 10 Evening
16:00 – 18:00 Symposium 9
Ca2+ signaling and synaptic transmission
Chairs: Markus Missler (Germany) and Martin Heine (Germany)
Ralf Schneggenburger (Switzerland) Mechanisms of ultrafast transmitter release at CNS synapses
Martin Heine (Germany) Calcium channel mobility as a variable of synaptic transmission
Gerald W. Zamponi (Canada) Regulation of calcium channels by ubiquitination
Markus Missler (Germany) Calcium channels and neurotransmitter receptors as target molecules of α−neurexin-based complexes
18:00 – 18:20 Coffee Break
18:20 – 20:20 Symposium 10
Coupling excocytotic neurotransmitter release to endocytic membrane retrieval
Chair: Volker Haucke (Germany)
Stephan J. Sigrist (Germany) Shedding light on active zone structure and function
Jürgen Klingauf (Germany) Coupling of exo- and compensatory endocytosis
Ling-Gang Wu (USA) Post-fusion structural changes and their roles in exocytosis and endocytosis
Volker Haucke (Germany) Mechanisms of pre-synaptic membrane retrieval and synaptic vesicle reformation
Friday
April 11 Morning
08:15 – 09:00 Keynote Lecture 3
Christopher Harvey (USA) Neuronal circuit dynamics during navigation-based decision tasks
09:00 – 11:00 Symposium 11
From circuits to behavior: Sensorimotor interactions in neural processing
Chair: Georg Keller (Switzerland)
Bence ölveczky (USA) Motor cortex independent skill execution
Adam Kampff (Portugal) Moving with cortex:
New techniques for studying behaviours that require motor cortex
Dinu Albeanu (USA) Understanding the roles of cortico-bulbar feedback in encoding odor identity
11:00 - 11:20 Coffee Break
11:20 - 13:20 Symposium 12
Multiple Sclerosis: New vistas
Chair: Frauke Zipp (Germany)
Ralf Gold (Germany) New therapies
Bernhard Hemmer (Germany) New antigens
Heinz Wiendl (Germany) New cellular pathways
Frauke Zipp (Germany) Novel mechanisms and targets in Multiple Sclerosis
Friday
April 11 Evening
16:00 - 16:45 Keynote Lecture 4
Bill Hansson (Germany) Coding good and bad odors in the Drosophila olfactory system
16:45 – 17:05 Coffee Break
17:05 - 19:05 Symposium 13
Cellular trafficking in the brain
Chair: Matthijs Verhage (The Netherlands)
Angus Silver (UK) Vesicle mobility and supply at a central excitatory synapse
Matthias Kneussel (Germany) Transport and trafficking of neuronal proteins underlying synaptic plasticity
Frederic Saudou (France) Huntingtin: Linking energy supply to axonal transport and neurotrophin signaling
Matthijs Verhage (The Netherlands) Trafficking and fusion of dense core vesicles in mammalian CNS neurons
19:30 Gala Dinner (free for Das Central hotel residents, others book at registration desk for 50,- € until Thursday evening)
Saturday
April 12 Morning
08:15 – 09:00 Keynote Lecture 5
Ole Kiehn (Sweden) Neural circuits for controlling rhythmic movements
09:00 – 09:30 Coffee Break
09:30 – 11:30 Symposium 14
Tracing neural processing hierarchies in auditory function, from synapse to perception
Chairs: Jan Schnupp (UK) and Yale Cohen (USA)
Benedikt Grothe (Germany) GABAergic
mechanisms underpin sub-millisecond precision in mammalian binaural hearing
Kasia Bieszczad (USA) A mnemonic function of primary auditory cortical remodeling to predict the significance of sound
Jan Schnupp (UK) How the brain creates and encodes pitch and timbre percepts for complex sounds
Micah Murray (Switzerland) The speed of sound in the human brain
11:30 End of meeting and departure
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Posters
Wednesday
April 9
19:05 - 20:30
1. Mitochondrial contributions to neuronal autophagy: Links to energetics and mitophagy?
Shin YS, Britto JM, Ryall JG, Higgins GC, Devenish RJ, Nagley P and Beart PM
2. Response to trauma and abuse presenting with overactivity, impulsivity and distractibility that is not secondary to severe ADHD symptoms but the fight and flight response, implications for treatments
Klaus Martin Beckmann
3. Visual speech gestures modulate efferent auditory system
Aravind Namasivayam, Dinaay Sharma, Wing Yiu Stephanie Wong, Dimitra Chaldi, Pascal van Lieshout
4. Left-right asymmetry is required for the habenulae to respond to both visual and olfactory stimuli
Elena Dreosti, Nuria Vendrell Llopis, Matthias Carl, Emre Yaksi and Stephen W. Wilson
5. Can GAP-43 be an early marker of neuronal stress? In vivo imaging and immunofluorescence study of GAP-43 after ischemic brain lesion
S. Gajovic, I. Bohacek, D. Gorup, T. Milicevic, J. Kriz
6. Tissue oxygen measurement for patients with brain injury
R. Gal, M. Slezak, M. Smrcka, A. Mrlian, M. Colonova
7. Distribution and roles of the Onecut transcription factors in spinal dorsal interneurons
K.U. Kabayiza, G. Masgutova, V. Rucchin and F. Clotman
8. Activation of cannabinoid receptor 1 induces ramification in primary microglia cells through activation of the signaling cascade PKCε-Src/Fyn-Raf-ERK1/2
Aikaterini A. Kalargyrou and Dimitra Mangoura
9. LH stimulation could potentiate the effect of inefective dose of morphine and induce morphine sensitization
Sara Karimi, Abbas Haghparast, Mahtash Baniardalan, Sara Sadeghi, Alireza Omranifard
10. Contrast normalization in cat primary visual cortex
Andreas Keller, Nuno Maçarico da Costa, Kevan A. C. Martin
11. Cav1.4 IT mouse as model for vision impairment in human congenital stationary night blindness type 2
Dagmar Knoflach, Verena Burtscher, Gerald J. Obermair, Martin Glösmann, Mathias Seeliger, Amy Lee, Klaus Schicker and Alexandra Koschak
12. Network dynamics in resting state EEG of youths with Autism Spectrum Disorder
Bates, E., Seitzman, B., Coppers, K., and Malaia, E.
13. Cortical plasticity following perceptual learning
Ido Maor and Adi Mizrahi
14. Effects of loud noise exposure on sound processing in the mouse primary auditory cortex
Ondřej Novák, Ondřej Zelenka, Tomáš Hromádka, and Josef Syka
15. Study of proteins associated with epileptic seizures in primary hippocampal cultures under basal and stimulated conditions
Austin O’Reilly
16. Role of KV channels in activity-dependent biphasic changes of Schaffer collateral fiber volleys
Benjamin Owen
17. Modulating synaptic function through neurexophilin/alpha-neurexin complex formation
Astrid Rohlmann
18. Activation of GABA A receptors of medial prefrontal cortex produces anxiolytic-like response
Jalal Solati, Ramin Hajikhani, Gunther H. Mol l, Oliver Kratz, Yulia Golub
19. Prion protein facilitates synaptic vesicle release by enhancing release probability
Susan W. Robinson, Marie L. Nugent, David Dinsdale and Joern R. Steinert
20. Disruption of the circadian system in patients with neuropsychiatric disorders
Sumová A., Nováková M., Sládek M., Nevšímalová S., Praško J.
21. Lateralization of language function in epilepsy patients: An event-related potential (ERP) study of a word/pseudoword task
Karin Trimmel, Ekaterina Pataraia, Gerald Lindinger, Marlene Weberberger, Judith Ifkovits, Eduard Auff, and Michael Trimmel
22. Neuronal expression of complex gangliosides is necessary for the maintenance of axon and axo-glial junction integritiy
R. McGonigal, D. Yao, J.A. Barrie, H.J. Willison
23. Ca2+-binding Calmyrin 2 functions in endocytosis in hippocampal neurons
Potrzebowska K, Błazejczyk M., Jaworski J., Kuźnicki J., Hoogenraad C.C., Wojda U